©CAAT

December 9, 2021 | Virtual Conference


Welcome

Thomas Hartung, CAAT, Johns Hopkins University, United States

Keynote Address: Advancing Alternative Methods at FDA

Donald Ingber, Wyss Institute, Harvard University, United States

MPS Hardware and Enabling Technologies (4 talks selected form submitted abstracts)

  • Early and Late Calcific Aortic Valve Disease-on-a-chip | Melissa Mendoza, Binghamton University, United States
  • Multi-Organ System for the Evaluation of efficacy and off-target toxicity of Anti-Cancer Therapeutics | Christopher W. McAleer, Hesperos, Inc., United States
  • A machine-learned microvasculature optimizes physiological insulin secretion in a vascularized pancreas-chip | James Tronolone, Texas A&M University, United States
  • Microphysiological system (MPS) platforms with high operability and pumping capability for commercialization | Kenta Shinha, Tokai University, Japan

Cell Models and Applications for MPS (4 talks selected form submitted abstracts)

  • Microgravity-Induced Mitochondrial Dysfunction in Human iPSC-Based 3D Cardiac Microphysiological System | Devin Mair, Johns Hopkins University, United States 
  • Synovial Joint-on-a-chip System for Modeling Osteoarthritic Features and Predicting Drug Efficacy | Megan LaFollette, Zhong (Alan) Li, University of Pittsburgh, United States 
  • Modelling T Cell-Vasculature co-culture in a high-throughput microfluidic platform | Michelle Brouwer, MIMETAS, The Netherlands
  • Engineering the neurovascular unit in vitro to improve drug delivery to the brain | Colette Bichsel, Roche, Switzerland

Panel Discussion and Q&A

Moderator | Adrian Roth, Roche, Switzerland

  • Linda Griffith, Massachusetts Institute of Technology, United States
  • Alysson Moutri, University of California San Diego, United States
  • Peter Loskill, Tuebingen University, Germany
  • Uwe Marx, TissUse, Germany
  • Hiroshi Kimura, Tokai University, Japan